Our micro-array data revealed that a large number of genes were differentially expressed in chordoma tissues, including EGFR [35, 36], PDGFRβ [37], IGF-1R [38, 39] and MET [40, 41] etc., which have been identified to the potential therapeutic targets in chordoma with both clinical and molecular evidence. This evidence concerns the gene PDGFRB and chordoma.