It has been shown that miR-145 expression is negatively correlated with the levels of Oct4/Sox2/Fascin1 in lung adenocarcinoma and an Oct4(high)/Sox2(high)/Fascin1(high)/miR145(low) phenotype, as in the present study, predicted poor prognosis [37]. The gene discussed is POU5F1; the disease is lung adenocarcinoma.