PIP4K2A and acute lymphoblastic leukemia: Associations reached genome-wide statistical significance (i.e., P < 5.0 × 10−8 in an additive logistic regression analysis) at known ALL risk loci, including: ARID5B, IKZF1, PIP4K2A, and CEBPE among Latinos, and ARID5B, IKZF1, and PIP4K2A for non-Latino whites (Supplementary Table 2).