For example in human CRC expression changes in a plethora of other cell adhesion genes have been reported, including induction of P-cadherin (CDH3)30, OB-cadherin (CDH11), claudins (CLDN1/2) and desmosomal proteins (DSC3, DSG2) and downregulation of CLDN5/8/23, DSC2, and protocadherins (PCDHB7/14)31. Here, CDH3 is linked to colorectal carcinoma.