IGHE and eosinophilic esophagitis: Meanwhile, this murine model also showed the elevation of eosinophil numbers accumulated in their oesophagus, lung, and small intestine tissues as well as the elevation of disease related chemokines, cytokines, or other mediators, the promotion of allergen specific IgE and IgG1, suggesting the pathogenesis of EoE like food allergy disease is similar to EoE animal model food allergy established by Rajavelu et al. 21.