In the older mice (15 to 24 months), visible tumor nodules were seen in 57% (16/28) (p < 0.001) and 71% (15/21) (p < 0.001) of MGL+/− and MGL−/− mice, respectively, whereas only 3 out 20 (12%) wild-type (MGL+/+) animals had visible tumor nodules (Fig. 1a). This evidence concerns the gene MGLL and neoplasm.