On the other hand, both qPCR (Fig. 7A-D) and western blot (Fig. 7E, 7F) assays confirmed that NKILA suppressed activation of several NF-κB target genes including CCND1, TWIST1, MMP9 and XIAP, all of which play vital roles in cancer growth and metastasis. The gene discussed is XIAP; the disease is cancer.