SEMA3C and posterior cortical atrophy: To determine the effects of SEMA3C on growth and castration resistance of PCa cells, LNCaP cells (which express low levels of SEMA3C) were stably transduced with a lentiviral vector (Naldini et al, 1996) expressing full‐length SEMA3C (LNCaPSEMA3C‐FL) or an empty vector (LNCaPempty) as a control.