In the benign lesions, the positive expression rates of UGP2 in the samples with chronic pancreatitis, adenoma, and epithelial neoplasia were 15.0% (3/20), 25.0% (5/20), and 20.0% (3/15), respectively; the positive expression rates for CFL1 in the chronic pancreatitis, adenoma, and epithelial neoplasia samples were 20.0% (4/20), 20.0% (4/20), and 26.7% (4/15), respectively. The gene discussed is CFL1; the disease is chronic pancreatitis.