An array of mutations (e.g., non-sense, frameshift, missense) in the gene encoding proline-rich transmembrane protein 2 (PRRT2) are linked to a wide group of paroxysmal disorders, including paroxysmal kinesigenic dyskinesia (PKD), benign familial infantile seizures, infantile convulsions with choreoathetosis, and episodic ataxia (Gardiner et al., 2015). Here, PRRT2 is linked to episodic kinesigenic dyskinesia 1.