Similarly, ablating CRH neurons with DTA did not impact anxiety-like behavior (DTA: 18.9 ± 1.7% time in center; Control: 18.9 ± 1.8% time in center), nor was locomotor activity in the open field test altered (DTA: 3441 ± 224 basic movements; Control: 3088 ± 161 basic movements) (Fig 5). This evidence concerns the gene CRH and Anxiety.