Cerulein induces an acute edematous pancreatitis, which in rats with normal GH secretion is reduced in its severity and producing a faster regeneration of the pancreas, being reduced the serum concentrations of the pro-inflammatory interleukin 1-β (IL-1β) and the serum activities of pancreatic enzymes amylase and lipase. This evidence concerns the gene GH1 and pancreatitis.