BDNF and myeloid sarcoma: Among the multiple molecular mediators involved in such effects, we discussed the role of Treg induction, the control of pro-oxidant chemical species, the limitation of deleterious pro-inflammatory mediators, the modulation of gene expression, the inhibition of COX-2 and the induction of BDNF, as well as other biological processes that could be responsible for the actions of C-PC and PCB on the recruitment, differentiation and maturation of OPCs in demyelinated lesions present in MS and IS.