Emerging AKI biomarkers, including NGAL, L-FABP, IL-18, and TIMP-2/IGFBP7, are reported to be useful for the early detection of AKI and prediction of progression because AKI impacts the metabolism and excretion of these biomarkers that are produced, excreted, or reabsorbed in the renal tubules [14, 18, 37, 42–47]. This evidence concerns the gene IL18 and acute kidney injury.