Emerging AKI biomarkers, including NGAL, L-FABP, IL-18, and TIMP-2/IGFBP7, are reported to be useful for the early detection of AKI and prediction of progression because AKI impacts the metabolism and excretion of these biomarkers that are produced, excreted, or reabsorbed in the renal tubules [14, 18, 37, 42–47]. Here, TIMP2 is linked to acute kidney injury.