The mechanism of action, by which adiponectin exerts its influence on the metabolic indices and androgen excess in the overweight PCOS women, include probable reduction of adiponectin serum levels as well as a reduction in the expression of adiponectin receptors in theca cells of PCOS patients due to the defective action of adiponectin [27]. Here, ADIPOQ is linked to polycystic ovary syndrome.