Two WT1 peptides, the HLA-A*02-restricted peptide 126–134 and the HLA-A*24-restricted peptide 235–243, have been tested in clinical trials and have been shown to be well-tolerated, safe and capable of inducing immunogenic and molecular responses both in the setting of complete remissions (CR) and in active AML and high-risk MDS [9–11]. Here, WT1 is linked to acute myeloid leukemia.