MAGEA3 and plasma cell myeloma: Rapoport et al. [26] demonstrated that combination of Montanide/poly ICLC/MAGE-A3 protein had greater antibody responses and better CTL responses in patients with multiple myeloma but was complicated with severe injection-site reactions that evolved into sterile abscess, but the MAGE-A3 alone without Montanide group still elicited clinical responses.