In a gerbil global cerebral ischemia/reperfusion injury model, Cao et al. examined the mRNA and protein expressions of BDNF in ischemic hippocampus by real-time RT-PCR and Western blot, respectively and found that treatment with baicalin remarkably promoted the expression of BDNF at mRNA and protein levels [46]. The gene discussed is BDNF; the disease is brain ischemia.