In addition, acteoside has significant protective effect on a cellular model of AD induced by okadaic acid through improving SK-N-SH cell morphology, enhancing cell survival rate, decreasing cell lactate dehydrogenase release rate and the expression of phosphorylated tau proteins at the p-Ser 199/202 and p-Ser 404 sites, and up-regulating the expression of non-phosphorylated tau proteins at the Ser 202 site and Ser 404 sites [109]. The gene discussed is MAPT; the disease is Alzheimer disease.