TP53 and colorectal carcinoma: The discrepancy from our observation may stem from the fact that in their analysis Zeilstra et al. included tumors with all p53 mutations types in the same group, whereas, we divided the examined CRC tumors to two groups: (1) tumors expressing p53 missense mutations that are known for their oncogenic functions and (2) tumors expressing WTp53 or p53 insertion/deletion mutations that usually exert loss of function.