We measured the density of glutamatergic (VGLUT1, VGLUT2, PSD95, and EAAT2), GABAergic (VIAAT and somatostatin) and cholinergic (choline acetyl transferase; ChAT) markers, as well as α-tubulin and synaptophysin, in BA9 samples from 171 individuals stratified according to the clinical dementia rating scale (CDR). The gene discussed is SYP; the disease is dementia.