The results showed that high INPP4B cohort had significant shorter OS (median, 14.3 vs 22.5 months; p = 0.02, Fig. 7a) and the three-year EFS (median, 14.3 vs 22.5 months; p = 0.02, Fig. 7b), compared with low INPP4B cohort of AML patients. The gene discussed is INPP4B; the disease is acute myeloid leukemia.