IP-10 (or C-X-C motif chemokine (CXCL)-10) is a chemokine induced by IFN-γ, which has been consistently found to be elevated in different stages of HIV infection, including acute/early infection, and it has been mostly associated with the worst-case scenarios in terms of disease progression [15,39,46,47,48,49,50,51]. This evidence concerns the gene CXCL10 and HIV infectious disease.