CD3+ pan T cells, CD4+ helper T cells, and CD8+ cytotoxic T cells are mainly found within the stromal compartment, CD25+CD4+FOXP3+ regulatory T cells border the tumor cells, and CD68+ macrophages and CD16+ natural killer cells make up the majority of the tumor infiltrating population within the tumor [72]. The gene discussed is FOXP3; the disease is neoplasm.