Given that YAP promotes TEA domain family member 1 (TEAD)-mediated transcription of cell cycle genes, such as CCND1 and FOXM1, one study found that silencing YAP in mesothelioma resulted in suppression of these genes and inhibition of cell motility, invasion and anchorage-independent growth [40]. This evidence concerns the gene CCND1 and mesothelioma.