To further investigate the prognostic value of CFL2, we performed data mining in the Kaplan–Meier plotter platform and found that high CFL2 mRNA expression is associated with worse OS (hazard ratio (HR) = 1.41; 95% confidence interval (CI): 1.08–1.84; p = 0.012) (Figure 8A) and worse FP (HR = 1.39; 95% CI: 1–1.92; p = 0.047) (Figure 8B) for patients with GC, suggesting that CFL2 is an unfavorable prognostic factor for GC. The gene discussed is CFL2; the disease is gastric cancer.