INS and cancer: Figure 5 shows the enriched relationships identified between these two sets of data, and highlights possible intermediates between them. Of interest were the intermediates ‘fatty acid oxidation’ and ‘insulin’. Upon investigation of the literature underpinning these connections (this can be done easily in MELODI which links directly to the articles in PubMed), we found that carnitine can increase fatty acid oxidation16–18. Metabolic reprogramming is a known feature of cancer cells,19 and fatty acid oxidation can be used by cancer cells for energy generation.20