Multiple hypothesis correction identified 9 transcripts with FDR<0.20; C21orf15, CYP1B1, FLT3, XKR3, SLC12A7, PAM, IL8, FBN1, and GPC4. Although this correction effectively reduced the number of significant transcripts, it may be more beneficial to retain all 82 significant transcripts in the aneurysm-associated signature at this early stage of discovery. The gene discussed is PAM; the disease is aneurysm.