The one who was investigating a neuroprotective effect of VEGF found that elderly patients (72.8 ± 3.2 years of age) with normal pressure hydrocephalus demonstrated a significant increase of VEGF (range: 10–70 pg/mL) in the CSF post-exercise as compared to no exercise controls (total sample size, 17 patients) [9]. The gene discussed is VEGFA; the disease is Hydrocephalus.