Ovarian cancer cells can recruit and induce the expansion of regulatory T cells (Tregs), which are able to inhibit the anti-tumor response of effector CD8+ T cells, either by secretion of interleukin-10 (IL-10) and transforming growth factor-β (TGF-β) or via a cell-cell contact-dependent mechanism. The gene discussed is IL10; the disease is ovarian carcinoma.