NDC80 expression is significantly correlated with tumor invasion, lymph node and distant metastasis (P = 0.041, P = 0.013 and P = 0.015), but not with other features including gender, age, tumor location, colon tumor location, tumor size, and tumor differentiation (P = 0.678, P = 0.520, P = 0.733, P = 0.381, P = 0.602, and P = 0.264). This evidence concerns the gene NDC80 and colonic neoplasm.