The multivariate analysis further reveals NDC80 expression, tumor differentiation, tumor invasion, lymph node metastasis, and distant metastasis were independent significant prognostic factors for both CSS and DFS (CSS: P = 0.009, P = 0.016, P = 0.024, P = 0.021, P < 0.001; DFS: P < 0.001, P = 0.004, P = 0.032, P = 0.001, P < 0.001, Table 3). The gene discussed is NDC80; the disease is metastatic malignant neoplasm in the lymph nodes.