CPEB4 and neoplasm: It can be challenging to attribute a specific role for CPEBs in disease since they are involved in complex regulatory loops, however these data show that CPEB4 has a direct role in tumor vascularization and metastasis (Ortiz‐Zapater et al., 2011), while post‐transcriptional regulation mediated by CPEBs has been shown to directly regulate tumor‐specific transgene expression (Villanueva et al., 2017).