In search of genetic markers of myocardial infarction (MI) risk, which haveprognostic significance for Russians, we performed a replication study of MIassociation with genetic variants of PCSK9 (rs562556),APOE (epsilon polymorphism, rs7412 and rs429358), LPL(rs320), MTHFR (rs1801133), eNOS(rs2070744), and the 9p21 region (rs1333049) in 405 patients with MIand 198 controls. The gene discussed is LPL; the disease is myocardial infarction.