We and others published findings that strongly support these observations and show that TGFβ not only blocks neutrophil cytotoxicity [3] but also induces an immunosuppressive N2 neutrophil phenotype [19] and that TGFβ receptor deficient myeloid cells, including neutrophils, maintain an anti-tumor phenotype and limit tumor growth [32]. The gene discussed is TGFB1; the disease is neoplasm.