HT29(US) human colon cancer cells transduced with either (sh-Scramble) or (sh-Cav1(#5)) containing lentivirus were treated for 48 h either with Methotrexate or Etoposide, washed and then injected intraperitoneally (1x106) into BalbC/NoD/SciD mice. Here, CAV1 is linked to colonic neoplasm.