These molecules mimic the BH3 domain of Bad, a sensitizer BH3-only protein thereby disrupting Bcl-2/Bim complexes and releasing Bim from the hydrophobic cleft of Bcl-2, which then results in Bax/Bak-mediated apoptosis in cancer cells but not in healthy cells [8, 9]. The gene discussed is BAK1; the disease is cancer.