AKT1 and acute myeloid leukemia: Pathway analysis of those 42 PCGs showed that “Transcriptional misregulation in cancer” was the most enriched pathway (P = 1.11E-7), followed by “Pathways in cancer” (P = 2.83E-3), “PI3K-Akt signaling pathway” (P = 8.32E-3), “Cytokine-cytokine receptor interaction” (P = 0.01), “Acute myeloid leukemia” (P = 0.019), and “Central carbon metabolism in cancer” (P = 0.024) (Figure 2A).