TLR4 and Sepsis: Sepsis risk was associated with TLR4 (toll like receptor 4) SNPs, rs4986790 and rs4986791 [5], but not the SERPINE1 [Serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1] rs1799768 polymorphism [6].