We analyzed 24 bladder cancer tissue sample pairs and found that ETS1 and BAX were up-regulated (3.7417±1.1395, 2.7592±1.2276 Fold respectively, P<0.01), whereas MYC, EGR1, SLC39A6, and ITGB1 were down-regulated (2.2163±0.1357, 3.8834±0.1242, 1.9277±0.1792 and 2.0565±0.1459 Fold respectively, P<0.01) in bladder cancer CD44highvs. CD44low tissue cells (Figure 6). The gene discussed is ITGB1; the disease is urinary bladder carcinoma.