Elevated ERCC1 (HR = 2.1, 95% CI: 1.1–3.9) [22], DKK1 [23], CXCL12 [24], long non-coding RNA MALAT-1 (OR = 3.65, 95% CI: 1.86–7.18) [25] in tissue sample, and detection of circulating tumor cells (pooled HR: 2.36, 95% CI 1.41–3.96) [26] in peripheral blood were risky factors for patients survival. Here, DKK1 is linked to neoplasm.