EYA1 is overexpressed in Wilms’ tumors [37], EYA2 is overexpressed in epithelial ovarian cancers and lung carcinoma [15, 18, 38], and EYA4 overexpression has been detected in MPNST (malignant peripheral nerve sheath tumor) [39]. The gene discussed is EYA2; the disease is malignant peripheral nerve sheath tumor.