For the SNPs − 21A>T CAT (rs7943316), − 262C>T CAT (rs1001179), and 47C>T SOD2 (rs4880), we identified differences between people with obesity CR (homozygous plus heterozygous) of mutated allele, and obese WT people, with respect to anthropometric and clinical variables in a cross-sectional study [26, 27]. The gene discussed is SOD2; the disease is obesity due to melanocortin 4 receptor deficiency.