CAT and Obesity: On the other hand, even if there is a great probability that several SNPs are involved in the observed final physiological response in subjects under a dietary intervention, the SNPs − 21A>T CAT (rs7943316) and 47C>T SOD2 (rs4880) reported in the present work could be used in future studies as a genetic tool to improve the treatment of overweight and obesity as well as to identify, trace, and evaluate the risk to develop several comorbidities of obesity.