With the progression of CKD stages, age, smoking pack-year, rates of hypertension, diabetes, CV disease, use of beta blockers, calcium channel blockers, diuretics, pulse pressure, PWVs, serum levels of phosphorus, hsCRP, and UPCR increased, but alcohol drinking, serum levels of calcium, bilirubin, albumin, and hemoglobin decreased (Table S1). This evidence concerns the gene ALB and chronic kidney disease.