MCM expression has been reported in the tumors that showed CDC7 overexpression such as OSCC, breast cancer cell line and tissue and also SGTs.15, 16, 17, 18 MCM2 and MCM3 represented an overexpression in malignant SGTs in comparison with benign ones17, 18 which indirectly support the overexpression of CDC7 in our samples. This evidence concerns the gene MCM3 and breast carcinoma.