Among those identified SNPs, the SNP rs11191548, located near the 3′ noncoding region of the gene CYP17A1 encoding the cytochrome P450 enzyme CYP17A1as a key enzyme involved in steroid metabolism, showed a significant association with hypertension in European adults, Japanese and Chinese adults, and Chinese children [6–9]. Here, CYP17A1 is linked to hypertensive disorder.