Genes related to the most represented lymphocyte (CD8, CD4, CD20, CD138) and macrophage (CD68) cell populations were expressed at a much higher level and frequency compared to genes related to immune cell subsets, like NK cells (NKp46), conventional DC (CD1a), and pDC (BDCA2), that are known to be minor components of MS brain immune infiltrates [8, 10, 12]. The gene discussed is CD8A; the disease is myeloid sarcoma.