The file also provides several figures: 1) images of high and low E-cadherin immunohistochemistry staining in tumor tissue specimens (Additional file 2: Figure S1), and 2) graphical comparisons of predicted probabilities based only on established diagnostic tests to predicted probabilities based on E-cadherin added to established diagnostic tests (Additional file 2: Figures S2-S5). The gene discussed is CDH1; the disease is neoplasm.