To investigate if the expression of STAT3 by myeloid cells could modulate T cell priming during infection with M. tuberculosis T cell receptor transgenic T cells specific for the immunodominant mycobacterial Ag85B240-254 peptide (p25-tg) cells were inoculated i.v. into stat3fl/fllysm cre or stat3fl/fl mice 17 days after infection with M. tuberculosis (Fig 3D). This evidence concerns the gene STAT3 and infection.