FLT3 and acute myeloid leukemia: It is being evaluated in 20 clinical trials, in mono and combined therapy, involving, for example, patients with newly-diagnosed acute myelogenous leukemia (NCT01873495), with relapsed/refractory acute myeloid leukemia carrying FLT3-ITD (NCT03170895), with myelodysplastic syndrome (NCT02159872), and in combined therapy with imatinib mesylate (NCT00114959), with quizartinib (NCT03135054) and with cytarabine and idarubicin (NCT02440568).