Our previous studies demonstrated that glyceollins produced in raw soybeans and exposed to various kinds of stress, including fungal infection and ultraviolet irradiation, induce antioxidant enzymes such as HO-1 and NAD(P)H:quinone oxidoreductase in an Nrf2-dependent manner and exert direct antioxidant activity [2,3]. This evidence concerns the gene NFE2L2 and fungal infectious disease.