The current study also revealed a higher vaspin serum concentration in patients with ACS previously and currently treated with rosuvastatin compared with patients with ACS not previously and currently treated by statins; this result is supported by the 2011 study by Kadoglou et al., which revealed that the pleiotropic effects of statin may increase vaspin serum levels in patients with ischemic heart disease [27]. The gene discussed is SERPINA12; the disease is coronary artery disorder.