To assess the roles of AP4 in tumour growth in vivo, AP4‐mediated tumorigenesis was examined in a murine xenograft model induced by LAPTM4B and AP4 control cells (LNAN), stable Huh7 cells with LAPTM4B overexpression (L+AN), stable Huh7 cells with AP4 knockdown (LNA−), or Huh7 cells with both AP4 knockdown and LAPTM4B overexpression (L+A−) cells. Here, TFAP4 is linked to neoplasm.